Genomics

Our Publications on Genomics

Craddock, J., Jiang, J., Patrick, S. M., Mutambirwa, S. B. A., Stricker, P. D., Bornman, M. S. R., Jaratlerdsiri, W., & Hayes, V. M. (2023). Alterations in the epigenetic machinery associated with prostate cancer health disparities. Cancers, 15(13), 3462. https://doi.org/10.3390/cancers15133462

Craddock, J., Lutsik, P., Soh, P. X. Y., Louw, M., Hasan, M. M., Patrick, S. M., Mutambirwa, S. B. A., Stricker, P. D., Förtsch, H. E. A., HEROIC PCaPH Africa1K, Bornman, M. S. R., Gerhäuser, C., & Hayes, V. M. (2025). Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities. bioRxiv. https://doi.org/10.1101/2025.04.16.649098

Gong, T., Jaratlerdsiri, W., Jiang, J., Willet, C., Chew, T., Patrick, S. M., Lyons, R. J., Haynes, A. M., Pasqualim, G., Brum, I. S., Stricker, P. D., Mutambirwa, S. B. A., Sadsad, R., Papenfuss, A. T., Bornman, R. M. S., Chan, E. K. F., & Hayes, V. M. (2022). Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers. Genome Medicine, 14(1), 100. https://doi.org/10.1186/s13073-022-01096-w

Gong, T., Jiang, J., Uthayopas, K., Bornman, M. S. R., Gheybi, K., Stricker, P. D., Weischenfeldt, J., Mutambirwa, S. B. A., Jaratlerdsiri, W., & Hayes, V. M. (2025). Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men. Nature Communications, 16(1), 2400. https://doi.org/10.1038/s41467-025-57312-9

Hayes, V., Jaratlerdsiri, W., Jiang, J., Gong, T., Patrick, S., Willet, C., Chew, T., Lyons, R., Haynes, A., Pasqualim, G., Louw, M., Kench, J., Campbell, R., Chan, E., Wedge, D., Sadsad, R., Brum, I., Mutambirwa, S., Stricker, P., Bornman, R., & Horvath, L. (2021). African-specific prostate cancer molecular taxonomy. Research Square. https://doi.org/10.21203/rs.3.rs-1122619/v1

Hayes, V., Jiang, J., Tapinos, A., Huang, R., Bornman, R., Stricker, P., Mutambirwa, S., Wedge, D., & Jaratlerdsiri, W. (2024). Kataegis associated mutational processes linked to adverse prostate cancer presentation in African men. Research Square. https://doi.org/10.21203/rs.3.rs-4597464/v1

Huang, R., Bornman, M. S. R., Stricker, P. D., Simoni Brum, I., Mutambirwa, S. B. A., Jaratlerdsiri, W., & Hayes, V. M. (2024). The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities. Scientific Reports, 14(1), 7706. https://doi.org/10.1038/s41598-024-57566-1

Lin, H. M., Mak, B., Yeung, N., Huynh, K., Meikle, T. G., Mellett, N. A., Kwan, E. M., Fettke, H., Tran, B., Davis, I. D., Mahon, K. L., Zhang, A., Stockler, M. R., Briscoe, K., Marx, G., Crumbaker, M., Stricker, P. D., Du, P., Yu, J., Jia, S., … Horvath, L. G. (2021). Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase. EBioMedicine, 72, 103625. https://doi.org/10.1016/j.ebiom.2021.103625

Peters, T. J., Meyer, B., Ryan, L., Achinger-Kawecka, J., Song, J., Campbell, E. M., Qu, W., Nair, S., Loi-Luu, P., Stricker, P., Lim, E., Stirzaker, C., Clark, S. J., & Pidsley, R. (2024). Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNA methylation profiling. BMC Genomics, 25(1), 251. https://doi.org/10.1186/s12864-024-10027-5

Soh, P. X. Y., Adams, A., Bornman, M. S. R., Jiang, J., Stricker, P. D., Mutambirwa, S. B. A., Jaratlerdsiri, W., & Hayes, V. M. (2025). Y chromosome variation and prostate cancer ancestral disparities. iScience, 28(5), 112437. https://doi.org/10.1016/j.isci.2025.112437

Wu, S. Z., Roden, D. L., Al-Eryani, G., Bartonicek, N., Harvey, K., Cazet, A. S., Chan, C. L., Junankar, S., Hui, M. N., Millar, E. A., Beretov, J., Horvath, L., Joshua, A. M., Stricker, P., Wilmott, J. S., Quek, C., Long, G. V., Scolyer, R. A., Yeung, B. Z., Segara, D., … Swarbrick, A. (2021). Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis. Genome Medicine, 13(1), 81. https://doi.org/10.1186/s13073-021-00885-z

Yamaguchi, T. N., Houlahan, K. E., Zhu, H., Kurganovs, N., Livingstone, J., Fox, N. S., Yuan, J., Sietsma Penington, J., Jung, C. H., Schwarz, T., Jaratlerdsiri, W., van Riet, J., Georgeson, P., Mangiola, S., Taraszka, K., Lesurf, R., Jiang, J., Chow, K., Heisler, L. E., Shiah, Y. J., … Boutros, P. C. (2025). The germline and somatic origins of prostate cancer heterogeneity. Cancer Discovery, 15(5), 988–1017. https://doi.org/10.1158/2159-8290.CD-23-0882